A monthly injection of buprenorphine BUP-XR is more effective than placebo for treating opioid addiction, according to the results of a new study. This formulation is the extended release version.
A daily dose version of buprenorphine was approved by the FDA (US Food and Drug Administration) in 2002. It has been an effective treatment for opioid use disorder. Daily doses mean patients must commit to taking it each day; they may start to experience cravings for opioids once they get close to the end of the 24-hour cycle when they can take more medication.
Medication Assisted Therapy for Opioid Addiction
Buprenorphine and methadone are both used in MAT (Medication Assisted Therapy) to treat opioid addiction. These medications are used in combination with behavioral counseling as part of a “whole patient” approach. The medications are used to control cravings and clients work with a counselor to develop new ways of thinking and responding to life stresses.
Extended Release Buprenorphine Called Sublocade
The extended-release version of buprenorphine was approved by the FDA in November 2017, which is being marketed under the brand name Sublocade. Approval was based on positive results in a Phase III human subjects study. The study has been published in The Lancet to make it available to the wider scientific community.
Double Blind Study Conducted
Researchers divided 200 participants in the randomized, double-blind study into three groups. All of them had a mean duration of opioid use of between 11 and 12 years. Two of the groups were given different monthly doses of BUP-XR and one was given a placebo.
Both groups who were given BUP-XR reported “substantial portions of participants” abstaining from opioids. They also experienced relief from withdrawal symptoms and control from cravings for opioids without having to take medication on a daily basis.
You have taken the first steps toward recovery by looking into drug treatment centers in Arizona, but now you face some difficult questions. If you are stuck wondering “Should I tell my employer I’m going to rehab? And if so, how?” you are on a good path toward recovery already. In general, the answer is yes, you should be honest about your situation.
Remember that getting treatment is a good thing.
You are more likely to keep your job in the long term if you seek treatment by going to rehab than if you continue to struggle with addiction on your own. If your addiction has been affecting your work, for example with poor work performance, spotty attendance, or compromised decision-making skills, you will be far more likely to improve the quality of your work after receiving treatment than if you continue repeating the same mistakes. It may even be a relief for your boss to know any erratic behavior you’ve been exhibiting has a cause and that you are working on a solution.
How do I tell my employer I’m going to rehab?
Be honest. If your boss or coworkers already suspect something is up with you, it will be much less suspicious if you are up front about going to rehab rather than adding extra layers of lies and deceit to cover it up. Being honest also makes you come across as a responsible person taking initiative for your health. Not to mention, if someone at work finds out you have lied and are actually at a drug treatment center in Arizona, that does not bode well for your future at the company.
If your boss allows it, schedule a one-on-one meeting so you don’t have to rush through the conversation at an inopportune time during the workday. If privacy is important to you, emphasize that you need discretion. Make your needs clear, but be respectful of company time and your boss’s schedule.
Understand your rights as an employee.
Before taking any official action, check company policy to see if rehab is protected or addressed. It may fall under your legally-protected sick leave, which guarantees you will have a job to come back to. Some companies offer counseling or related help with finding an addiction treatment center. Even if your company’s policy does not address rehab specifically, an open and honest conversation with your boss or a human resources manager should help you understand your options. If you lie about where you are for the duration of your absence, your leave might not be legally protected, and that could put your job in jeopardy.
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Don’t be embarrassed.
Every employee struggles with something, but not everyone is capable of reaching out for help and seeking treatment. The fact that you are taking active steps to better yourself is a strong mark in your favor.
Understand that some people may react poorly to your announcement. That is okay. You can feel assured that you are making a healthy decision for yourself by choosing to get well, and that indirectly means you are making the best choice for your company as well. Stand your ground and do not let anyone pressure you into not seeking treatment. You are doing the right thing.
Take some initiative to plan ahead.
Get as many important, time-sensitive projects finished as possible before you leave. Explain your job functions to a close colleague, so if the company has to bring on a temporary replacement while you are gone, you are helping to ensure a smooth transition. This extra effort and concern for the company’s time and money will cast you in a more favorable light than if you were to leave without much notice or preparation.
Do not feel pressured to explain everything.
You do not owe anyone, including your boss, a detailed explanation of your situation or your choices. You are not on trial; you are simply notifying your employer that you will be taking leave.
If you feel you are in a position where you simply cannot be honest and up front about where you will be going, that’s okay. Your health and recovery are more important. Do what you need to do in order to attend rehab and get healthy, and worry about the rest later.
Many treatment facilities offer job assistance at the end of your stay, so you do not have to feel like your job is the only option in the world. If your current opportunity ends, you will find another when you are healthy.
What is a good drug treatment center in Arizona that can help me?
Desert Cove Recovery offers a helping hand through every step of your recovery journey, starting with detox and ending with extended care for long-term help. Whether your preference lies with the classic twelve step treatment or with more holistic methods, Desert Cove Recovery will make every effort to address your unique needs as an individual.
There is no need to fear being cooped up in a hospital room for weeks on end. Spending time in nature with the Outdoor Therapy program gives you time to take in the fresh air and the beautiful Arizona scenery while you get back on your feet.
Top 10 Myths of Sober Living and What Sober Living is Like
The path to sobriety is rarely a straight one. Treatment options range from local support groups to inpatient treatment centers. In the middle are sober living homes, offering individuals a drug and alcohol free residence where they may focus weaning themselves from harmful substances. Unfortunately, the myths of sober living and what it is actually like are preventing patients from considering sober living homes.
Below is a list of the top 10 myths often associated with sober living homes. Although there is always the exception to every rule, or in this case myth, most sober living homes are helping individuals find their path to sobriety. A sober living home may be the most effective option for you or a loved one struggling with addiction.
1. Sober Living Homes Are Always In Bad Neighborhoods
Local non-profit organizations or government programs often supported the first sober living homes. With limited funding, homes were established where it was more cost-effective at the time. This meant homes were opened in less desirable neighborhoods where the property values were more affordable.
However, as the stigma of addiction shifted, overall funding increased, and the introduction of private treatment facilities grew, so too did the establishment of sober living homes in more comfortable areas. Today you will find sober living homes in nearly every type of neighborhood. From the inner cities to the posh suburbs, finding a sober living home in a neighborhood of your liking has never been easier.
2. Poor Maintenance Plagues Sober Living Homes
When fixated on the myth that all sober homes are in bad neighborhoods, the likely vision most individuals will have is that of a dilapidated house in need of dire repair. Although some homes may indeed require attention, the privatization of sober living homes has meant companies need to attract new patients to survive.
The need to attract new patients has shifted sober living homes from having been treatment centers of last resort to now becoming the first choice patients seek to become sober. The more inviting a sober home is, the more likely to attract clients and the funding needing to keep the doors open.
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3. Sober Living Homes Are Not Regulated
While it may be true that sober living homes might not receive the same scrutiny as other medically related residences such as assisted living or nursing homes; they are far from being unregulated. Depending on local ordinances, governments consider most sober living homes either apartments or short-term living accommodations (like a hotel).
In either instance, the laws and regulations for such facilities are much more stringent than if the local government consider the location simply a single-family home. Further, if any medical services were provided by the sober home on premises, additional regulations would apply.
4. Drug Use is Common in Sober Living Homes
While every sober living home has their own set of rules, the ultimate goal of sober living is to provide a place removed from the temptations of the outside world. Many sober living homes subject residences to random drug tests.
How a particular sober living home resident responds to a positive drug test determines the perceived leniency toward drug use. Rules related to drug or alcohol use can range from soft to strict. For example, an individual caught using a banned substance may only be required to seek counseling. More strict locations may ask individuals to leave entirely.
5. Safety is Concern in Sober Living Homes
Sober homes exist to help suffering individuals from all walks of life. There are indeed facilities who will welcome former criminals as they work to transition back into society. Such homes are beacons of hope for those whose addiction may or may not be directly connected to their criminal activity.
While some sober homes accept all individuals regardless of history, others are more restrictive on who they accept. On the other hand, there are sober living homes that specialize in working specifically with individuals who have had run-ins with the law. Ultimately, it is the sober home’s responsibility to keep their residents safe. Consider the home’s safety record just as you would any other residence you might consider.
6. Pets are Not Allowed
The decision whether to allow pets entirely rests with the sober home. Although it is true many locations will not allow pets of any kind, more homes are opening up allowing pets on-site. Caring for a pet can help promote responsible behaviors as well as providing a loving companion for someone in recovery. Researchers are exploring the benefits caring for a pet might have for those recovering from addiction.
7. Most Sober Living Homes are Full
New sober living homes are opening all the time. The best run facilities are able to accept new residents almost immediately. If space is not immediately available, most sober living homes are a part of a larger network that can assist in placement very quickly. Treatment professionals understand recovery success is partially dependent on how fast an individual can be enrolled and begin treatment when they feel ready to start.
8. Residents are Not Allowed to See Family or Friends
The support of family and friends is a critical aspect of addiction recovery. Nearly all sober living homes allow visitations from those who care about you. There may be, however, restrictions and rules governing when and how often residents may receive visitors. Often visitors must be approved by the sober living home’s manager while the resident has to meet certain progress milestones. In some circumstances, program rules may allow residents may be to leave the home overnight.
9. It Is Free to Live in a Sober Living Home
Most sober living homes charge rent. A few homes may receive charitable assistance or government subsidies, but more homes are now privately owned and have developed a rent schedule based upon the services provided, number of residents, and length of stay.
There are sober living homes who do not charge their residents. However, most often these homes are for individuals who do not have any financial means to pay rent. Once residents begin to hold down a job, rent will be required of them.
10. All Sober Living Homes Are the Same
Sober living homes come in a variety of different program types. Individuals seeking recovery, along with their counselors, can select the best program to fit their needs including:
For people who suffer from certain mental illnesses or come from a correctional facility, locked residences are also available. However, the differences between sober living homes go way beyond the type of residence. Residences can be very simple in style providing basic living facilities, to high-end luxury apartments.
Choosing a Sober Living Home
Separating the myths of sober living and what it is actually like is an important first step in continuing the journey to clean living. Sober living through Desert Cove Recovery teaches residents how to address the root causes of their addiction. Counseling and therapy are provided in a comfortable, substance-free environment, allowing residents to realize the meaning and purpose of their lives. We have inpatient services in our network ready to work with you or your loved one to receive the most effective treatment.
Approximately 20 percent of people who take Xanax, Valium and other benzodiazepines (benzos) are not using them as directed by their doctor, according to the results of a US survey. The results also show that adults are using this potentially-addictive medication more than twice as often as previously reported.
Nearly 13 percent of those surveyed said they had used benzos within the past 12 months.Studies conducted in 2013-14 estimated that four-six percent of adults were taking them.
What are Benzodiazepines?
Benzodiazepines are prescribed by doctors to treat anxiety and panic attacks, along with insomnia. Drugs in this class commonly produce a sedative effect in patients and can also cause weakness or unsteadiness.
Approximately 25.3 million adults stated they used benzodiazepines as prescribed by their doctor during the past year. The researchers said they were surprised to discover that middle-aged respondents (between ages 50-64) are taking benzodiazepines more often than any other age group. Just over 14 percent reported they had used this class of drugs during the previous year.
Another 5.3 million respondents said they had misused their medications. Misusing a prescription means using it in a way other than directed by a doctor, including taking a higher dose, taking it more often or longer than prescribed.
Benzodiazepine Misuse Common Among Young Adults
Lead researcher Dr. Donovan Maust commented that young adults in the 18-25 age group are most likely to misuse benzodiazepines. He is an assistant professor at the University of Michigan’s Department of Psychiatry. Dr. Maust said that misuse for this type of drug is “as common as prescription use,” which he described as being disturbing.
Overdose Deaths due to Benzos “Snowballed” in Last 10 Years
These survey results, which were published in the journal Psychiatric Services, are similar to reports released earlier in 2018 which warned that overdose deaths related to benzodiazepines have snowballed over the past decade. The overdose rate coincides with a steady increase in prescription rates for this class of drugs.
Benzodiazepine-related overdoses increased sevenfold in the years 1999-2015, jumping from 1,135 to 8,791 deaths. These figures originally appeared in the New England Journal of Medicine (February 2018).
New research conducted by a team at the University of Maryland School of Medicine in Baltimore has identified a neural pathway that is linked to addiction and depression. Their findings, which were recently published in the journal Nature, found an increased intensity of signals passing between the hippocampus and the nucleus accumbens.
Pleasure and Reward System Governed by the Brain
The pleasure and reward system is one of the most important systems that the brain regulates in humans. It gives us the “nudge” we need to eat, drink and be sexually active. All these activities are needed to ensure the continued survival of our species.
The way the reward system operates is also an important factor in many types of addictive behavior.
Professor Scott Thompson, Ph.D., the leader of the research team, stated that the two parts of the brain (the hippocampus and the nucleus accumbens) are known to be important in processing rewarding experiences for humans. He went on to say that the communication between the two is stronger in a case of addiction, although the underlying mechanisms were unknown to the team.
Team Tests Depression Hypothesis
The research team tested a new hypothesis: whether the same signals became weaker in people living with depression. Since one symptom of depression is anhedonia (a loss of pleasure in usually pleasurable activities), the researchers wanted to discover whether weakening signals in the neural pathways could be the underlying cause of depressed patients.
Using mice, the team focused on brain circuitry that plays an important role in goal-oriented behavior. They wanted to see if they could change the animals’ activity. They added light-sensitive proteins into the neurons forming the brain’s circuitry. Once this step was completed, the researchers hoped to control the signals by blocking or boosting the levels between the hippocampus and the nucleus.
The researchers created a false reward memory in the mice that received the light-sensitive protein by exposing them to light during a four second period. This meant the mice learned to associate pleasure with the location where they felt light exposure.
After a day, the researchers took the mice back to the place where they had received the false memory of associating pleasure with light and exposed them to light again. The goal was to shut down the signal between the hippocampus and the nucleus accumbens this time, however.
They confirmed this pathway is critical to the way the brain is wired for reward association. Once the pathway is shut down, the mice stopped liking the location where they originally received the reward memory.
Next, the researchers looked at depression. They tried to boost brain activity in depressed mice but this part of the experiment wasn’t successful. The researchers had to administer antidepressants to the mice before they could imprint any artificial reward memories in the brain of depressed mice.
Dr. E. Albert Reece, the dean of the University of Maryland School of Medicine, said these are exciting results that will bring us closer to understanding what’s happening in the brains of clinically depressed patients.
After declaring the US in the midst of a public health emergency in 2017 due to the opioid crisis, The President signed a bill into law that experts believe will help to curb the opioid crisis. The new legislation is called the SUPPORT for Patients and Communities Act.
More Funding for Addiction Treatment
The new law provides funding to federal agencies and states so that they can provide increased access to addiction treatment. It also puts measures in place to help alleviate the crisis, such as:
• Preventing overprescribing • Training law enforcement agencies to intercept drug shipments at US borders
The bill signing was the culmination of a 12-month effort by the legislative and executive branch to react to the opioid crisis. While lawmakers said the bill was a step in the right direction, although many of them said it didn’t go far enough to deal with the epidemic. Rep. Frank Pallone of New Jersey cautioned of ramifications of talk of reducing access to publicly-funded treatment programs.
Congress and the White House entered into discussions for making a plan for confronting the epidemic in October 2017. This was before several congressional hearings by the House and the Senate on the same subject.
Public health experts have spoken out in favor of the bill, since it increases access to treatment. They say this is a critical step to controlling the epidemic. One of the measures in the legislation removes an old measure that didn’t allow clients with substance abuse issues get treatment in mental health facilities with more than 16 beds under Medicaid.
Private Companies on Board with New Initiatives
The White House has also pointed to new initiatives from private companies:
• Amazon has programmed its Alexa voice service to answer consumers’ questions about opioids and addiction. • Blue Cross Blue Shield, the major insurance provider, will establish a national toll-free phone number to help US residents locate drug and alcohol treatment centers. • Biopharmaceutical company Emergent BioSolutions will offer free Narcan nasal sprayers at over 16,500 public libraries and 2,700 YMCAs. Narcan, when administered to someone experiencing an opioid overdose, can help reverse the condition.
Treatment Still the Main Focus
What this new law and other efforts do is to help continue to focus on the need for treatment at all levels. This current drug crisis won’t subside until there are enough people seeking and receiving quality treatment for their substance use disorders. Desert Cove Recovery is proud to be a leader in rehabilitation for people both in Arizona and from all over the country.
The results from a new report released from the Centers for Disease Control and Prevention (CDC) published in the CDC’s Morbidity and Mortality Weekly Report shed light on the continued effects of the opioid epidemic on a specific portion of the population: pregnant women. The researchers found that the number of women living with opioid use disorder at the time they went into labor and delivered their babies “more than quadrupled” during the 15-year period between 1999-2014.
Opioid use at addiction levels during pregnancy has been linked to several negative health consequences for mothers and babies. The drug use can lead to preterm birth, stillbirth and neonatal abstinence syndrome (NAS), a term describing a group of conditions caused when a fetus goes through withdrawal from certain drugs before birth.
National Database Analyzed
Researchers analyzed a national database collected on women from 28 states and discovered the rate of opioid use disorder jumped from 1.5/1000 delivery hospitalizations in 1999 to 6.5/1000 delivery hospitalizations in 2014. The rate increased by 0.39 cases per 1,000 during each year of the study.
Some geographical differences were noted during the study. The average annual increases were highest in West Virginia, Vermont, New Mexico and Maine. They were lowest in Hawaii and California.
Wanda Barfield, MD, Rear Admiral, US Public Health Service (USPHS), and the Director of the Division of Reproductive Health, explained that even in states with the smallest increases year over year, more pregnant women with opioid use disorder are being seen in labor and delivery.
Strategies for Dealing with Opioid Addiction in Pregnancy
The report included strategies for states to take on the issue of opioid addiction in pregnancy.
Ensure opioid prescribing is in line with the CDC’s current guidelines
Intensify prescription drug monitoring programs.
Institute a policy of substance use screening at the first prenatal visit.
Make certain that pregnant women with opioid use disorder have access to MAT (medication assisted therapy) and other addiction treatment services.
Provide mothers with opioid use disorder with postpartum care that includes substance abuse treatment, mental health treatment, relapse prevention and family planning services.
The opioid epidemic continues to rage through North America, and experts in East Tennessee are looking into the source of the problem. Many of them have determined that it can start with a trip to the dentist’s office.
Dr. Turner Emery, an oral surgeon on Knoxville, explained that doctors have been blamed for a lot of patients getting started on opioids. However, dentists also prescribe this class of medications to their patients, who are also put at risk for addiction.
Exparel Given at Time of Surgery
Dr. Emery is using a medication in his practice called Exparel to reduce risk of opioid addiction. It numbs the area around teeth that have been extracted for up to four days after oral surgery has been performed. When Exparel is used, a dental surgery patient may not need prescription pain medication at all.
The peak time for a dental patient to experience pain following wisdom teeth removal is on the second and third day following surgery, Dr. Emery explains. He has had a couple of patients who have had to take one or two doses of a narcotic, but most patients have been able to relieve their pain wth over the counter (OTC) medicines.
The medication is given by injection in each molar. Patients report that it reduces the need for narcotic pain medication and doesn’t make them feel drowsy during the first few days following their procedure.
First Exposure to Narcotics After Dental Surgery
A number of adolescents are first exposed to opioids following dental surgery. They may also be prescribed these strong pain medications following a sport injury. If a young person is prescribed more medicine than they need for the initial health condition, there is a concern that the opioid pain reliever may end up in someone else’s hands. The young person may continue taking the narcotic after the initial need for the strong pain medication has ended.
Medication Effective for Pain Relief
Exparel isn’t covered by all health insurance companies. The medication costs approximately $200.00, which can be a prohibitive factor for some patients and their families. Dr. Emery states that the medication works “really, really well” and that he has had good results with it.
People are Getting Naltrexone Implants for Opiate Addiction & Why Heroin Rehab Arizona is a Better Choice
Millions of people struggle with addiction and are desperate to get to the light at the end of the tunnel and a return to a life of normalcy. However, the path is usually not an easy one, and it is a journey that can be taken in one of many different ways. Some turn to heroin rehab Arizona for help to overcome their addiction, while other people take problems into their own hands by getting a naltrexone implant for opiate addiction.
What Are Naltrexone Implants and Why Are People Turning to Them to Treat Opiate Addiction?
Naltrexone is an opioid antagonist. Its prime benefit is that it blocks the effects on the brain of opioids such as prescription painkillers, heroin and other narcotic drugs.
Effects of opioids usually include a temporary escape from pain, stress and fear, which is why they can be so addictive. However, that escape never lasts as tolerance starts getting built after many uses. Eventually, the effects of the substance continue to decrease, getting to the point that taking it ends up being necessary just to feel normal. Now the person’s body relies on the drug to survive, instead of using it as a means of escape, resulting in a heavy drug addiction.
Many of those who are addicted to opioids are turning to naltrexone implants to help them overcome their addictions for a number of reasons. The primary benefit of naltrexone is that it blocks many of the opioid’s effects at the brain cell receptor levels, which results in the desired benefits being significantly reduced. Due to this effect, the opioid cravings are lessened, a definite help in overcoming an addiction.
Specifically, a naltrexone implant for opiate addiction consists of small medication pellets that go under the skin. They gradually release the naltrexone over a period of several months.
Implants, in particular, are preferred by many because they remove the risk of forgetting to take a pill, or even purposefully not taking a pill. Naltrexone can be a good option for those who have a history of relapsing as it decreases the desire for alcohol or opiates.
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Do Naltrexone Implants Work?
A naltrexone implant for opiate addiction does appear to help reduce opioid use. According to a 2009 study, patients participating in a study experienced 45 fewer days of heroin use and 60 fewer days of opioid use than those in the control group. Additionally, a 2014 systematic review of nine studies found that naltrexone implants were much more effective than the absence of them although it should be noted that “the quality of the evidence ranged from moderate to very low.”
Importance of Heroin Rehab Arizona
Although naltrexone implants are proven to help with addiction, there are several other ways to take control of your recovery. One thing that naltrexone does not help with are withdrawal symptoms. These can be significant and can include abdominal pain, agitation, anxiety, diarrhea, muscle cramps, nausea, sleep disturbances, sweating and vomiting. Heroin Rehab Arizona will help ensure that the withdrawal experience is handled as carefully as possible so that this part of the recovery process is overcome and is not as overwhelming to the patient as it might otherwise be.
Another reason why it’s important for those addicted to heroin to engage with a heroin rehab program is because the rehab process will address the underlying issues that led to addiction in the first place. Allowing this process to happen will ensure that the chances of recovery are permanent. Of course, relapses are always possible, but it’s important to keep the odds of those occurring as low as possible, and heroin rehab is the best way to make sure that this ends up being the case.
Naltrexone Doesn’t Cure Addiction
It should also be noted that naltrexone doesn’t cure any sort of addiction. It helps, of course, but it is not a be-all and end-all cure that many might be hoping for. The person addicted to opiates also needs to be motivated to recover. Simply taking naltrexone will not be enough if the desire and motivation is not there to overcome the drug use and to make that permanent.
Obviously, the same can be said of those in a rehab center, but, in that case, the support will be there to help the patient see that it is in his or her best interests to overcome this addiction. Of course, all that matters in the end is that the patient is motivated, and no support system, regardless of how strong, can ensure that will occur, but a rehab center will increase the odds of that happening.
If you or a loved one is suffering from an addiction to heroin or other opioids, contact Desert Cove Recovery, Heroin Rehab Arizona for assistance. Our experienced staff will assist you as you begin your journey to recovery.
FDA Approves Two Generic Medications for Opioid Dependence Treatment
Mylan Technologies Inc. and Dr. Reddy’s Laboratories SA have received the go-ahead to market buprenorphine and naloxone sublingual film. These products will be made available to patients as generic versions of Suboxone, a medication used to treat opioid dependence.
Buprenorphine is used to reduce the severity of opioid withdrawal symptoms. Naloxone blocks their effects and reverses the same. The two medications can be used as part of an overall treatment program that includes counseling and prescription monitoring.
More Help Available for Opiate Addiction
Generic buprenorphine and naloxone sublingual film will be available in several dosage levels. These medications can only be prescribed by medical professionals certified by the Drug Addiction Treatment Act.
Dr. Scott Gottlieb, the FDA Commissioner, stated that the FDA is taking steps to “advance the development of improved treatments for opioid use disorder” and to ensure that these medications are available to patients who need them. He also said that includes “promoting the development of better drugs, and also facilitating market entry of generic versions of approved drugs to help ensure broader access.”
About Medication-Assisted Treatment
Medication-assisted Treatment (MAT) is a treatment option that uses FDA-approved medications (buprenorphine, methadone or naltrexone) along with counseling and other types of behavioral therapies, to treat opioid addiction. This form of treatment reduces the severity of withdrawal symptoms. The medications used for MAT don’t give participants the “high” or feeling of ecstasy normally associated with opioid abuse, although some of these medications can wind up being abused as well, so they alone are not a permanent solution.
At an appropriate therapeutic dose for a patient, buprenorphine is also supposed to reduce the pleasurable effects he would experience if he took other opioids. This effect would make continued use of opioids less attractive, therefore much less likely.
Patients who are receiving MAT for opioid use disorder benefit from this type of treatment in another way as well: they cut their risk of dying by 50 percent, according to the Substance Abuse and Mental Health Services Administration (SAMHSA).